guy riding a bike illustration

Treatment Resistant Depression

Over 1/3 of patients suffering from Major Depressive Disorder experience treatment resistance.

This study is examining a treatment for clinically depressed patients who have experienced an inadequate response to at least one (but no more than three) antidepressants.

If you use antidepressants and are between 18 to 74 years old, you could qualify for this clinical research study.

dialogue icon

Medical Oversight

  • 24-hour access to MBR’s doctors/medical staff.
  • World class medical oversight.
  • Free of Charge!
like icon

Free of Charge!

  • Insurance is NOT required to participate.
  • Free services include:
    – Study related medication
    – Doctor’s visits
    – Physical exams
    – Testing
coins icon


  • Those who qualify and choose to participate may receive up to a $600 stipend.
Monroe Biomedical Research - Hero

“Its through research like this that we can find solutions for 30% of patients who suffer from treatment resistant Major Depressive Disorder.


Learn More
Register Today

The first step is to learn more and see if you qualify. After registering, a clinical research coordinator will contact you and answer your questions

Sign up using the link below

Call or text +1 704 283 7359


Visit Our Center
See If You Qualify

Our facility is state of the art.

Visit our center for a prescreening visit to see if you qualify.


What our Patients say about our services

Research facility

Monroe Biomedical


Square feet Dedicated Research Facility


Recreational Area Comfortable Recliners


Free entertainment options


First Class Service from our Nurses and Staff

Free entertainment

Movies and Shows
Personal Tablets
Large Flatscreen TV

High Speed Wifi

Family Friendly

Very Comfortable

FLU clinical study illustration

Treatment for Major
Depressive Disorder

The purpose of this study is to evaluate the efficacy of aticaprant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in adult participants with major depressive disorder (MDD) with moderate-to-severe anhedonia (ANH+) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI).

Click here for more information




Contact Us

Monroe Biomedical Research
343 Venus Street, Monroe, NC 28112

Office Phone: 704-283-7369
Fax: 704-283-7329


Frequently Asked Questions

What is clinical depression mean?
  • Clinical depression – also known as major depression or major depressive disorder – is a mood disorder characterized by a persistent feeling of sadness and loss of interest.
What happens in depression?
  • Depression is a mental disorder that can cause persistent sadness and loss of interest and lead to various emotional and physical problems. You may experience trouble thinking, concentrating, or remembering things.
What is the best treatment for depression or anxiety?
  • The best treatment for depression or anxiety may vary depending on the individual. However, some of the most common treatments for depression or anxiety include medication, therapy, and self-care.
What are the main effects of depression?
  • Besides causing mental problems, depression also shows opposing sides in physical appearance, like lousy sleep habits, weakened immune system, loss of appetite (or increased need with atypical depression), constant fatigue, and body pain.
How much will the study cost?
  • There will be zero costs for the study participant to take part in the Treatment for Major Depressive Disorder.
What if I am uninsured?
  • Proof of insurance is NOT required to participate in this study. All medical oversight over the course of your study participation is included.
What does investigational medication mean?
  • An Investigational medication (also known as investigational new drug) has been approved by the Food and Drug Administration (FDA) for testing in people in a clinical study, but has not been approved for general use, distribution or sale. It is through clinical research that these medications receive full approval by the FDA.
How will I be compensated for participating?
  • Participants receive a check following each study visit. For this study, those that qualify and choose to participate could receive a total payment of up to $600.