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Charleston, SC (Dedicated)
Monroe Biomedical Research, 4975 Lacross Road, Suite 200-B, North Charleston, SC 29406MBR Charleston is a respiratory-focused clinical research site with strong internal medicine capabilities, specialized staff, and rapid startup support. -
Charleston, SC (Embedded Pediatrics Clinic)
Monroe Biomedical Research, 2781 Tricom Street, North Charleston, SC 29406MBR's Charleston embedded clinical research site pairs strong pediatric and adolescent clinical depth with experienced investigator leadership, specialized research staff, and a patient-focused approach to complex protocol execution. -
Louisville, KY
Monroe Biomedical Research, 3288 Illinois Avenue, Louisville, KY 40213MBR’s Louisville site is a prolific metabolic research facility with Phase 1–4 capabilities and strong central operational support. -
Monroe, NC (East Building)
Monroe Biomedical Research, 343 Venus St, Monroe, NC 28112MBR’s Monroe East Building is a dedicated overnight and early-phase research facility with Phase 1 infrastructure, serial sampling support, and 24-hour operational coverage. -
Monroe, NC (West Building)
Monroe Biomedical Research, 343 Venus St, Monroe, NC 28112MBR’s Monroe West Building is a high-efficiency outpatient clinical research site supported by Monroe campus infrastructure, quality systems, and recruitment resources.
Featured Investigators
MBR's principal investigators are clinically engaged physicians with research experience, therapeutic depth, and established participant relationships. Across the network, they help support high-quality study conduct, informed participant care, and reliable execution for Sponsors and CROs.
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Awawu E. Igbinadolor, MD
Dr. Awawu E. Igbinadolor is a highly accomplished Principal Investigator with broad experience across internal medicine clinical trials. At Monroe Biomedical Research, she has led studies across respiratory disease, diabetes, hypertension, Alzheimer’s disease, and COVID-19 research. She has completed more than 100 trials across diverse therapeutic areas and is experienced with first-in-human, dose-escalation, SAD/MAD, crossover, and adaptive designs in early Phase 1 trials. Dr. Igbinadolor is a strong fit for general medicine trials, with deep experience in cardiometabolic, endocrine, respiratory, infectious disease, vaccine, and early-phase studies. -
Claire Presswood, MD
Claire Presswood, MD, is a board-certified Internal Medicine physician, Diplomate of the American Board of Obesity Medicine, and Principal Investigator with years of clinical trial experience. She has been an investigator on over 100 clinical trials, with research interests in obesity, diabetes, post-bariatric hypoglycemia, hypertension, hyperlipidemia, cardiovascular outcomes, MASH, vaccines, devices, healthy participant studies, and Phase 1-3 clinical trials. -
David W. Zub, MD
David Zub, MD, is board-certified with the American Board of Anesthesiology with an additional certification in Pain Management. He has also earned the Safe Opioid Administration REMS Certification. Dr. Zub has a broad range of experience in pain management, chronic pain from Complex Regional Pain Syndrome, Failed Back Surgery Syndrome and spinal cord stimulation. He is a member of several professional organizations, including the American Society of Regional Anesthesia and Pain Medicine (ASRA), the American Society of Anesthesiology (ASA), the American Academy of Pain Medicine (AAPM), the North Carolina Medical Society and the Pain Society of the Carolinas. -
Dustin C. Hoffman, MD
Dustin Hoffman, MD, is a board-certified and fellowship-trained Orthopedic Surgeon who treats both operative and non-operative conditions of the hip and knee. He believes in customized patient care plans tailored to meet the needs of each patient. Dr. Hoffman specializes in direct anterior hip replacements, bikini incision anterior hip replacements, outpatient total hip and knee replacements and complex total hip and knee replacements. He is fully credentialed in robotic-assisted joint replacement including partial knee, total knee, and total hip. An avid researcher and presenter throughout his medical training, Dr. Hoffman is a member of the American Association of Hip and Knee Surgeons, the American Academy of Orthopedic Surgeons and the American Medical Student Association. -
Gerald “Tad” Dryden, MD, PhD, MS, MSPH
Dr. Dryden is a board-certified gastroenterologist and Professor of Medicine at the University of Louisville, with clinical expertise in inflammatory bowel disease, Barrett's esophagus, celiac disease, and colon cancer screening, gained through decades of academic GI practice. -
Gregory Feldman, MD, CPI
Gregory Feldman, MD, is a triple-board-certified physician in Internal Medicine, Critical Care, and Pulmonology, with more than 30 years of experience working with pulmonary patients in clinical trials. Since 2007, he has completed more than 200 studies, with particular depth in respiratory, vaccine, and cardiometabolic research. He leads MBR Charleston as Principal Investigator and is a standout respiratory and pulmonology investigator. -
Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC
Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC, has served as Principal Investigator for more than 700 clinical trials of metabolic therapeutic interventions and is one of the strongest scientific differentiators across the MBR network. Hae was Medical Director and President of the Louisville Metabolic and Atherosclerosis Research Center, Inc. (L-MARC), which was acquired by MBR in 2025. He is a nationally recognized investigator for obesity, endocrinology, lipid disorders, cardiometabolic disease, and MASH/MASLD research. -
Jeremy J. Hoff, DO
Jeremy Hoff, DO is an expert in the implantation of devices that help patients manage their pain, including spinal cord stimulators. In addition to his training and experience in conventional treatments, he has extensive knowledge of alternative pain management techniques. Bringing additional expertise in the exciting new field of Orthobiologics, Dr. Hoff has a special interest in therapeutic injections using adipose (fat cells), PRP (platelet rich plasma) and bone marrow. -
Jeremy T. Hines, MD
Jeremy Hines, MD, is board certified in Orthopedics, and his primary areas of specialization include total hip and knee arthroplasty, including revisions, as well as treatment of periprosthetic joint infection and fractures, robotics and other new technologies in adult joint reconstruction. He is fully certified in Mako Robotic-Arm Assisted Surgery for total knee replacement. Throughout his medical training, he participated in numerous studies on issues related to joint replacement, and published many articles on his research. -
Keith Horvath, MD
Keith Horvath, MD, is an investigator with Monroe Biomedical Research in North Charleston, South Carolina. A board-certified surgeon with specialty training in cardiothoracic surgery, Dr. Horvath has decades of experience in cardiac and thoracic care, academic medicine, and clinical research. He earned his medical degree from the University of Chicago Pritzker School of Medicine and completed surgical training at Brigham and Women’s Hospital, with additional research training at Massachusetts General Hospital. His research background spans cardiovascular surgery, valve disease, CABG, atrial fibrillation, transfusion practices, renal protection, neuroprotection, and cardiac surgery outcomes. At MBR, he supports clinical research with a strong foundation in surgical expertise, patient care, and evidence-based medicine.
New at MBR
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MBR Welcomes Felicia Irvin as Chief Commercial Officer
We’re welcoming Felicia Irvin to MBR as Chief Commercial Officer. Felicia brings more than 15 years of experience in clinical research, with expertise spanning business development, operations, patient recruitment, and network growth. She has built her career by bridging commercial commitments with operational delivery. As CCO, she will lead MBR’s … Read more
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Monroe Biomedical Research Acquires L-MARC to Expand Therapeutic Expertise and Geographic Footprint
Monroe Biomedical Research (MBR), a leading clinical trial site network specializing in patient recruitment for complex clinical trials, has completed the acquisition of L-MARC (Louisville Metabolic and Atherosclerosis Research Center, Inc.), a nationally recognized clinical research site based in Louisville, Kentucky. Founded by Dr. Harold Bays, L-MARC has built a strong reputation … Read more
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Understanding and Managing Agitation in Alzheimer’s
Agitation in Alzheimer’s can signal discomfort, confusion, fear, pain, or an unmet need. Learn common triggers and practical caregiver strategies.